Several new randomized trials evaluating the effectiveness and safety of spinal manipulative therapies (SMT) have been published since our previous systematic review (SR). Therefore, we aim at updating the evidence base for the effectiveness of SMT for migraine. An update searches were performed in the following electronic databases: Amed, Embase, Medline, CINAHL, Mantis, Index to Chiropractic Literature, and Central using the exact same search terms that had previously been constructed over two concepts: SMT and migraine headache (without any methodological filters). In addition, bibliographies of all thus identified studies and relevant SRs were scanned for any relevant papers. We searched for English language papers but considered studies published in any language.